Synthesis of substituted quinolines from N-aryl-N-(2-alkynyl)toluenesulfona-mides via FeCl3-mediated intramolecular cyclization and concomitant detosylation

摘要

A series of substituted quinolines have been synthesized in moderate to good yields (55-81%) from easily available substrates N-aryl-N-(2-alkynyl)toluenesulfonamides via FeCl3-mediated intramolecular cyclization and concomitant detosylation.