An efficient copper mediated synthetic methodology for benzo[d]isothiazol-3(2H)-oees and related sulfur-nitrogen heterocycles

摘要

A copper mediated sulfur-nitrogen coupling reaction for the synthesis of benzo[d]isothiazol-3(2H)-ones and related sulfur-nitrogen heterocycles has been presented, which requires 2-halo-arylamides, sulfur powder, 25-50 mol % of copper iodide/1,10-phenanthroline, and potassium carbonate as base.