Solvent-free palladium-catalyzed phosphination of aryl bromides and triflates with triphenylphosphine

摘要

Palladium-catalyzed phosphination of substituted aryl bromides and triflates using triphenylphosphine as the phosphinating agent was developed using solvent-free conditions. This operationally simple method tolerates ketone, aldehyde, ester, nitrile and ether functional groups.