Asymmetric synthesis of diversely substituted N-hydroxyiipyrrolidines using cycloadditions with chiral nitrone enolate/ylids

摘要

A stereoselective synthesis of diversely subsituted N-hydroxypyrrolidines is repored, based on the cycloaddition reaction of chiral non-racemic nitrone ylids with a variety of #alpha#,#beta#-unsaturated esters.