Micropellet-loaded rods with dose-independent sustained release properties for individual dosing via the Solid Dosage Pen

Laukamp Eva Julia; Knop Klaus; Thommes Markus; Breitkreutz Joerg

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Micropellet-loaded rods with dose-independent sustained release properties for individual dosing via the Solid Dosage Pen

机译：通过固体剂量笔进行单个剂量给药的微丸负载棒具有独立于剂量的持续释放特性

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摘要

Individual dosing of medicines is relevant for paediatrics, geriatrics and personalised medicine. The Solid Dosage Pen (SDP) allows for individual dosing by cutting monolithic, tablet-like drug carriers of pre-defined heights.

机译：个体用药与儿科，老年病和个性化药物有关。固体剂量笔（SDP）可以通过切割预先确定高度的整体式，片状药物载体来进行单独给药。

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来源
《International Journal of Pharmaceutics》 |2016年第2期|共9页
作者
Laukamp Eva Julia; Knop Klaus; Thommes Markus; Breitkreutz Joerg;
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正文语种 eng
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关键词
Individual dosing; Solid Dosage Pen; Multiparticulate dosage form; Micropellets; Sustained release;

机译：单独给药;固体笔;多颗粒剂型;微丸;缓释;

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专利

1. Micropellet-loaded rods with dose-independent sustained release properties for individual dosing via the Solid Dosage Pen [J] . Laukamp Eva Julia, Knop Klaus, Thommes Markus, International Journal of Pharmaceutics . 2016,第1a2期

机译：通过固体剂量笔进行单个剂量给药的微丸负载棒具有独立于剂量的持续释放特性
2. Individual Oral Therapy with Immediate Release and Effervescent Formulations Delivered by the Solid Dosage Pen [J] . Eva Julia Laukamp, J#xF6, rg Breitkreutz, Journal of Personalized Medicine . 2012,第4期

机译：固体剂量笔提供的具有速释和泡腾剂配方的个体口服治疗
3. Evaluation of Lipophilic Properties of Thermoplastic Granule in Formulation of Sustained Release Matrix in Solid Dosage Forms [J] . Pourmand Mahmood Reza, Shariat Farshid Pajoum, Ardjmand Mehdi Pharmaceutical Chemistry Journal . 2019,第7期

机译：实体剂型中持续释放基质制剂中热塑性颗粒的亲脂性能评价
4. Lack of Dose Flexibility in Solid Oral Controlled-Release Dosage Forms [C] . G.A. Green, C. Berg, N. Valdez Annual meeting exposition of the Controlled Release Society . 2009

机译：口服控制释放剂量形式的剂量灵活性不足
5. Development of a sustained release injectable suspension dosage form of buprenorphine. [D] . Yu, Shipeng. 2006

机译：丁丙诺啡的缓释注射剂悬浮剂的研制。
6. Individual Oral Therapy with Immediate Release and Effervescent Formulations Delivered by the Solid Dosage Pen [O] . Klaus Wening, Eva Julia Laukamp, Markus Thommes, 2012

机译：固体剂量笔提供的立即释放和泡腾剂配方的个体口服治疗
7. Individual Oral Therapy with Immediate Release and Effervescent Formulations Delivered by the Solid Dosage Pen [O] . Klaus Wening, Eva Julia Laukamp, Markus Thommes, 2012

机译：固体剂量笔提供的即时释放和泡腾配方的个人口服治疗
8. PREDICTION OF THE MAXIMUM DOSAGE TO MAN FROM THE FALLOUT OF NUCLEAR DEVICES IV. HANDBOOK FOR ESTIMATING THE MAXIMUM INTERNAL DOSE FROM RADIONUCLIDES RELEASED TO THE BIOSPHERE [R] . Yook C. Ng, C. Ann Burton, Stanley E. Thompson 1968

机译：从核装置的降落预测人类的最大剂量IV。用于估算放射性核素最大内部剂量的手册，发布到BIOspHERE

Micropellet-loaded rods with dose-independent sustained release properties for individual dosing via the Solid Dosage Pen

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