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Effects of limited medical resource on a Filippov infectious disease model induced by selection pressure

机译:有限医疗资源对选择压力致Filippov传染病模型的影响

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In reality, the outbreak of emerging infectious diseases including SARS, A/H1N1 and Ebola are accompanied by the common cold and flu. The selective treatment measure for mitigating and controlling the emerging infectious diseases should be implemented due to limited medical resources. However, how to determine the threshold infected cases and when to implement the selective treatment tactics are crucial for disease control. To address this, we derive a non-smooth Filippov system induced by selective treatment measure. The dynamic behaviors of two subsystems have been discussed completely, and the existence conditions for sliding segment, sliding mode dynamics and different types of equilibria such as regular equilibrium, pseudo-equilibrium, boundary equilibrium and tangent point have been provided. Further, numerical sliding bifurcation analyses show that the proposed Filippov system has rich sliding bifurcations. Especially, the most interesting results are those for the fixed parameter set as the bifurcation parameter varies, the sliding bifurcations occur sequentially: crossing. buckling. real/virtual equilibrium. buckling. crossing. The key factors which affect the selective treatment measures and the threshold value of infected cases for emerging infectious disease have been discussed in more detail. (c) 2016 Elsevier Inc. All rights reserved.
机译:实际上,SARS,A / H1N1和埃博拉等新兴传染病的爆发伴随着普通感冒和流感。由于医疗资源有限,应采取缓解和控制新发传染病的选择性治疗措施。但是,如何确定感染病例的门槛以及何时实施选择性治疗策略对于疾病控制至关重要。为了解决这个问题,我们导出了由选择性治疗措施引起的非光滑Filippov系统。全面讨论了两个子系统的动力学行为,并给出了滑移段,滑模动力学和不同类型的平衡(如正则平衡,拟平衡,边界平衡和切点)的存在条件。此外,数值滑动分叉分析表明,所提出的Filippov系统具有丰富的滑动分叉。特别是,最有趣的结果是固定参数集的结果,因为分叉参数变化,滑动分叉依次发生:交叉。屈曲。真实/虚拟平衡。屈曲。穿越。讨论了影响选择性治疗措施的关键因素和新发传染病感染病例阈值。 (c)2016 Elsevier Inc.保留所有权利。

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