Chiral Separations: Fundamental Review 2010

摘要

This fundamental review article covers developments and applications in chiral separations from January 2008 to January 2010 and is restricted to the English language literature. Judging from the number of articles and reviews appearing in the literature worldwide, it is clear that the study and application of chiral separations is soundly entrenched and used across a broad array of disciplines. From the number of papers published over the past two years, high performance liquid chromatography (HPLC) and capillary electrophoresis (CE) continue to be two of the most heavily utilized techniques. Between these two techniques, HPLC is by far the dominantly used method, with a conservative estimate of over 1000 publications appearing using chiral HPLC in numerous journals and languages. With the tremendous number of publications in this field, a comprehensive review of all published papers is not feasible; thus, this fundamental review focuses on major developments and trends in the field of chiral separations as well as representative applications.