A Novel Dinuclear Chiral Niobium Complex for Lewis Acid Catalyzed Enantioselective Reactions: Design of a Tridentate Ligand and Elucidation of the Catalyst Structure

摘要

Development of chiral catalysts for asymmetric reactions is one of the most important tasks in organic synthesis. While various types of catalysts have been developed, exploitation of novel catalysts, especially those based on unusual metals and novel ligands, applicable to new enantioselective reactions, is still very important. Herein we describe the first highly enantioselective niobium(V) Lewis acid catalyst.