functional characterization, localization, and molecular identification of rabbit intestinal N-amino acid transporter

摘要

The most important amino acid in the bloodstream is glu-tamine. It accounts for 20% of the total amino acid content in the human bloodstream beta5). Glutamine is the preferred substrate for the intestinal enterocytes. Glutamine is not only important for the functioning of the small intestinal enterocytes but also critical for mucosal cell integrity and gut barrier (17, 33). It is a precursor for the rapidly growing mucosal cell's nucleic acid and protein synthesis (7). Furthermore, as important as glutamine is for the normal small intestine, it may be even more important in pathophysiological states of the small intestine to help restore it back to health (12, 13, 18, 23, 32).