Gold-Catalyzed Intermolecular Synthesis of Alkylidenecyclopropanes through Catalytic Allene Activation

摘要

A stereoselective gold(I)-catalyzed intermolecular cyclopropanation of allenamides with stabilized sulfonium ylides is reported. This transformation enables the direct synthesis of diacceptor alkylidenecyclopropanes and proceeds under very mild conditions through allene activation.