Resveratrol may not offer health benefits to healthy women

摘要

A study published in Cell Metabolism shows that resveratrol, an ingredient in red wine thought to improve insulin sensitivity, reduce risk of heart disease, and increase longevity, may not offer these benefits in healthy women. The study involved 29 post-menopaus-al women who did not have type 2 diabetes and who were reasonably healthy. For 12 weeks, 15 took an over-the-counter 75-mg resveratrol supplement (the same as drinking 8 L of red wine), and the rest got a placebo, or sugar pill. The team measured the women's sensitivity to insulin and the rate of glucose uptake in their muscles, infusing insulin into their bodies and measuring their metabolic response to different doses. The researchers were unable to detect any effect of resveratrol. In addition, they took small samples of muscle and fat tissue from these women to look for possible effects of resveratrol in the body's cells, and again, could not find any changes in the signaling pathways involved in metabolism.