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首页> 外文期刊>Bioorganic and Medicinal Chemistry Letters >A novel D-glucose derivative radiolabeled with technetium-99m: synthesis, biodistribution studies and scintigraphic images in an experimental model of Ehrlich tumor.
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A novel D-glucose derivative radiolabeled with technetium-99m: synthesis, biodistribution studies and scintigraphic images in an experimental model of Ehrlich tumor.

机译:一种用tech 99m放射性标记的新型D-葡萄糖衍生物:在Ehrlich肿瘤的实验模型中的合成,生物分布研究和闪烁显像图像。

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摘要

A d-glucose-MAG(3) derivative was successfully synthesized and radiolabeled in high labeling yield. Biodistribution studies and scintigraphic images in Ehrlich tumor-bearing mice were performed. This compound showed high accumulation in tumor tissue with high tumor-to-muscle ratio. Thus, d-glucose-MAG(3) could be considered as agent for tumor diagnosis.
机译:d-葡萄糖-MAG(3)衍生物已成功合成并以高标记产率进行了放射性标记。进行了Ehrlich荷瘤小鼠的生物分布研究和闪烁显像。该化合物在肿瘤组织中具有高的肿瘤与肌肉比率,显示出高积累。因此,d-葡萄糖-MAG(3)可以被认为是肿瘤诊断的试剂。

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