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Investigation for extrahepatic shunt before SIRT by PET/CT with 68Ga-MAA.

机译:采用68Ga-MAA的PET / CT对SIRT前肝外分流的研究。

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摘要

Intraarterial application of ~99mTc-radio-labelled macroaggregated human serum albumin (MAA) into the hepatic artery is an integral part of patient evaluation before selective intraarterial radioembolisation (SIRT) of hepatic neoplasms in order to quantify 1. the hepatopulmonary shunt,2. possible dystopic extrahepatic flow and 3. regional intrahepatic distribution of particles.Classically, after angiographic application of the ~99mTc-MAA, static planar thoracic and abdominal scintigrams and hepatic SPECT are acquired. Mainly for purpose 2. of the evaluation, hybrid imaging of the abdomen would be desirable.We describe a case with pretherapeutic difficulties in the evaluation of single photon emission computed tomography (SPECT) imaging. This prompted an additional PET/CT after intraarterial injection of ~68Ga-MAA.
机译:在肝肿瘤的选择性动脉内放射栓塞(SIRT)之前,将肝内〜99mTc放射性标记的人类聚集的大白蛋白(MAA)动脉内应用到患者评估中是不可或缺的部分,以量化1.肝肺分流,2。可能存在的异位肝外血流和3.肝内颗粒的局部分布。通常,在〜99mTc-MAA血管造影应用后,可获得静态的平面胸腹腹部闪烁图和肝脏SPECT。主要用于评估目的2.腹部混合成像是可取的。我们描述了在评估单光子发射计算机断层扫描(SPECT)成像时治疗前困难的情况。动脉内注射〜68Ga-MAA后,这提示了另外的PET / CT。

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