The relationship between nailfold capillaroscopic assessment and telangiectasia score with severity of peripheral vascular involvement in systemic sclerosis

摘要

Systemic sclerosis (SSc) is a connective tissue disease characterised by autoimmune inflammation, vascular injury and fibrosis (1). Vascular injury starts in the early phases of the disease and can cause digital ischaemia-gangrene and pulmonary arterial hypertension (PAH) which were major factors of high morbidity and mortality in SSc. (2). Raynaud's phenomenon (RP) is accepted as the initial clinical symptom reflecting the microvascular injury before the onset of other manifestations (3,4).