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Pneumatosis intestinalis after allogeneic bone marrow transplantation for acute lymphocytic leukemia

机译:同种异体骨髓移植后急性肠淋巴细胞性肺炎

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A 45-year-old man was diagnosed as having acute lymphocytic leukemia (ALL) in February 1997. Complete remission was achieved by chemotherapy, and allogeneic BMT from his HLA-identical sister was performed on November 13, 1997. He developed acute GVHD (grade II), but quickly recovered after methyl-PSL pulse therapy. On June 5, 1998--day 202 after BMT--abdominal pain developed. X-ray and CT examinations showed pneumatosis intestinalis, pneumoperitoneum, pneumomediastinum and abdominal free air. We performed oxygen administration and methyl-PSL pulse therapy, and this quickly improved the symptoms. Corticosteroid and chronic GVHD were thought to be the causative factors of pneumatosis intestinalis in this case. Although pneumatosis intestinalis is relatively rare, it is one of the important potential complications that can occur after allogeneic BMT.
机译:一名45岁的男子在1997年2月被诊断出患有急性淋巴细胞性白血病(ALL)。通过化疗实现了完全缓解,并于1997年11月13日从他与HLA相同的妹妹进行了同种异体BMT。他患上了急性GVHD( II级),但在甲基PSL脉冲疗法后很快恢复。 1998年6月5日,即BMT结束后的第202天,出现腹痛。 X射线和CT检查显示肠肺气肿,气腹,肺纵隔和腹部自由空气。我们进行了输氧和甲基-PSL脉冲疗法,从而迅速改善了症状。在这种情况下,认为皮质类固醇和慢性GVHD是肠道尘肺的病因。尽管肠道尘肺病相对罕见,但它是同种异体BMT后可能发生的重要潜在并发症之一。

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