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高齢者(80歳以上)に対するCABGの治療戦略 クラフト選択を中心に

机译:老年人(80岁及以上)的CABG治疗策略以手艺选择为重点

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摘要

Octogenarians are at increased risk for perioperative morbidity and mortality after coronary artery bypass. This study is aimed to elucidate the suitable operative strategy and perioperative management. A retrospective analysis was conducted of 54 consecutive patients with 80-years of age or older, who underwent elective isolated coronary artery bypass between May 1999 and May 2008. Mean follow-up was 43.3 months and 96.3% complete. Operavive mortality was 3.7% and the incidence of stroke was 3.7%. The 7-year cardiac survival was 80.4% and the 7-year cardiac event free was 65.0% . The use of arterial graft to the right coronary artery was identified as independent predictor of late cardiac event Neither total arterial revascularization nor bilateral internal thoracic artery grafting was a significant cardiac event factor. This retrospective study suggests a benefit of the less invasive strategy in terms of operative mortality and morbidity. Application of fast-track treatment in octogenarians appears to be an effective approach to reduce perioperative morbidity and enhance long-term quality of life.
机译:八十岁以上的人在冠状动脉搭桥术后围手术期发病和死亡的风险增加。本研究旨在阐明合适的手术策略和围手术期管理。回顾性分析了1999年5月至2008年5月之间接受选择性隔离冠状动脉搭桥术的54例80岁以上的连续患者。平均随访43.3个月,完成了96.3%。手术死亡率为3.7%,中风发生率为3.7%。心脏7年生存率为80.4%,无心脏7年事件为65.0%。右冠状动脉的动脉移植被认为是心脏迟发事件的独立预测因子。总动脉血运重建和双侧胸廓内动脉移植均不是重要的心脏事件因素。这项回顾性研究表明,在手术死亡率和发病率方面,微创治疗策略具有一定优势。在八十岁以下儿童中应用快速治疗似乎是降低围手术期发病率并提高长期生活质量的有效方法。

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