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Audit of suspected meningitis in a district in 1996-1997 and in 1999.

机译:在1996-1997年和1999年对一个地区的疑似脑膜炎进行了审计。

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The Public Health Laboratory Service has published guidance outlining appropriate investigations and public health action to control the spread of meningococcal disease. We investigated compliance with this guidance in audits of suspected meningitis cases in our district notified to the public health department between January 1996 and December 1997, and in 1999. The total number of suspected meningitis cases in 1996-7 and in 1999 were 58 and 34 respectively. Meningococcal disease was suspected in 49 and 28 patients respectively, and for 58 (75.3%) of these case notes were found. Rash was more often a presenting sign in 1999. The second audit also showed a non-significant reduction in the proportion of patients given penicillin before hospital admission (22.4% vs. 7.1%, p = 0.12), and in CSF microscopy requests (31% vs. 17.6%, p < 0.5). Requests for meningococcal investigation by blood culture (77.5% vs. 79.4%, p < 0.5) blood PCR (34.5% vs. 64.7%, p < 0.001) and throat swab (25.9% vs. 55.9%, p < 0.005) were increased. Notifications of cases to the public health department within 24 hours of admission were also increased slightly (42.8% vs. 52.9%; p < 0.5). Changes in clinical practice can be achieved through guidelines, audit and feedback. The importance of parenteral penicillin administration prior to hospital admission, appropriate investigations and prompt public health notification should be re-emphasised.
机译:公共卫生实验室服务局已发布指南,概述了适当的调查和公共卫生行动,以控制脑膜炎球菌疾病的传播。我们调查了在1996年1月至1997年12月以及1999年间通知给公共卫生部门的我区疑似脑膜炎病例的审核中对本指南的遵守情况。1996-7年和1999年的疑似脑膜炎病例总数为58和34分别。分别怀疑49例和28例患有脑膜炎球菌病,其中58例(75.3%)被发现。皮疹通常是在1999年出现的迹象。第二次审核还显示,入院前接受青霉素的患者比例(22.4%比7.1%,p = 0.12)和CSF显微镜检查要求的比例无明显减少(31 %vs. 17.6%,p <0.5)。通过血液培养进行脑膜炎球菌调查的请求数量(77.5%vs. 79.4%,p <0.5)血液PCR(34.5%vs. 64.7%,p <0.001)和咽拭子(25.9%vs. 55.9%,p <0.005)有所增加。入院后24小时内通知公共卫生部门的病例也略有增加(42.8%对52.9%; p <0.5)。可以通过指南,审核和反馈来实现临床实践的改变。应再次强调在入院前进行肠外青霉素管理,进行适当的调查和及时进行公共卫生通知的重要性。

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