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Predicting the risk of anastomotic leakage in left-sided colorectal surgery using a colon leakage score

机译:使用结肠漏血评分预测左侧结直肠癌手术中吻合口漏的风险

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While much has been published in the literature regarding the risks for anastomotic leak, evidence-based tools to aid surgeons in deciding whether or not to create a defunctioning stoma after left-sided colorectal surgery are lacking. In an article recently published in the Journal of Surgical Research, Dekker et al. report a novel Colon Leakage Score (CLS) that may help guide surgeons in making this decision [11. The CLS estimates the probability of a clinically significant anastomotic leak from left-sided colorectal surgery defined as left colectomy, sigmoid resection, or rectal resection. The CLS was derived from the combination of a literature review and Delphi method and validated in a single-center retrospective study. The score is comprised of 11 weighted patient and operative risk factors, yielding a value between 0 and 43. Using receiver operating characteristic curves and logistic regression models, the CLS can be used to predict the probability of a clinically significant anastomotic leak in individual patients. Among the population studied, a CLS value of 11 corresponded to a 3% risk of leak.
机译:尽管有关吻合口泄漏风险的文献已经发表了很多,但仍缺乏基于证据的工具来帮助外科医生确定左侧结直肠癌手术后是否造成功能失调的造口。在最近发表在《外科研究杂志》上的一篇文章中,Dekker等人。报告一种新颖的结肠渗漏评分(CLS),可帮助指导外科医生做出此决定[11。 CLS估计了定义为左结肠切除术,乙状结肠切除术或直肠切除术的左侧结直肠癌手术发生临床上明显吻合口漏的可能性。 CLS源自文献综述和Delphi方法的结合,并在单中心回顾性研究中得到了验证。该分数由11个加权患者和手术风险因素组成,得出0到43之间的值。使用接收器操作特征曲线和logistic回归模型,CLS可用于预测个别患者发生临床上明显吻合口漏的可能性。在研究的人群中,CLS值为11对应于3%的泄漏风险。

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