BACKGROUND: In some countries, intraoperative histological evaluation to control the surgical margin for non-melanoma skin cancer is widely used instead of Mohs micrographic surgery. Nevertheless, this evaluation by frozen section analysis is usually limited to suspicious areas. OBJECTIVES: To evaluate the efficacy of double-bladed scalpel for intraoperative histological margin control for non-melanoma skin cancers. METHODS: Between 2005 and 2009, 10 basal cell carcinomas and 5 squamous cell carcinomas were underwent complete histological margin control in which a double-bladed scalpel was used during the surgery at the Hokkaido University Hospital in Japan. RESULTS: The mean number of re-excisions required for complete tumor resection was 1.4 times. Nine (60%) of the 15 patients obtained histological clearance of all surgical margins at the first re-excision. The mean size of total surgical margin was 6.1 mm (range: 2-12 mm). The median time from the first tumor excision to reconstruction was 124 min. No local recurrences have been reported. CONCLUSIONS: This method may be used as an alternative for complete histological margin control at many hospitals where it is difficult to perform Mohs micrographic surgery.
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