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首页> 外文期刊>Diabetes/metabolism research and reviews >Breastfeeding patterns of mothers with type 1 diabetes: results from an infant feeding trial.
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Breastfeeding patterns of mothers with type 1 diabetes: results from an infant feeding trial.

机译:1型糖尿病母亲的母乳喂养方式:婴儿喂养试验的结果。

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BACKGROUND: Both the initiation and maintenance of breastfeeding have been reported to be negatively affected by maternal type 1 diabetes (T1D). The aim of this study was to prospectively examine the breastfeeding patterns among mothers with and without T1D participating in a large international randomized infant feeding trial (TRIGR). METHODS: Families with a member affected by T1D and with a newborn infant were invited into the study. Those who had HLA-conferred genetic susceptibility for T1D tested at birth with gestation > 35 weeks and were healthy were eligible to continue in the trial. Among the 2160 participating children, 1096 were born to women with T1D and 1064 to unaffected women. Information on infant feeding was acquired from the family by frequent prospective dietary interviews. RESULTS: Most (>90%) of the infants of mothers with and without T1D were initially breastfed. Breastfeeding rates declined more steeply among mothers with than without T1D being 50 and 72% at 6 months, respectively. Mothers with T1D were younger, less educated and delivered earlier and more often by caesarean section than other mothers (p < 0.01). After adjusting for all these factors associated with the termination of breastfeeding, there was no difference in the duration of breastfeeding among mothers with and without T1D. CONCLUSIONS: Maternal diabetes status per se was not associated with shorter breastfeeding. The lower duration of breastfeeding in mothers with T1D is largely explained by their more frequent caesarean sections, earlier delivery and lower age and education.
机译:背景:据报道,母乳喂养的开始和维持均受到母亲1型糖尿病(T1D)的负面影响。这项研究的目的是前瞻性检查参加大型国际随机婴儿喂养试验(TRIGR)的有无T1D的母亲的母乳喂养方式。方法:邀请患有T1D疾病的成员和一名新生儿的家庭参加研究。那些在妊娠> 35周时出生时接受过HLA赋予的T1D遗传易感性且健康的人有资格继续进行试验。在参加活动的2160名儿童中,患有T1D的妇女出生了1096名,未受影响的妇女出生了1064名。通过频繁的前瞻性饮食访谈从家庭获得有关婴儿喂养的信息。结果:大多数(> 90%)有和没有T1D的母亲的婴儿最初都是母乳喂养的。母亲的母乳喂养率在六个月时分别比没有T1D的50%和72%下降得更厉害。患有T1D的母亲比其他母亲更年轻,受教育更少,更早通过剖腹产进行分娩(p <0.01)。在对与终止母乳喂养有关的所有这些因素进行调整之后,有和没有T1D的母亲的母乳喂养时间没有差异。结论:母体糖尿病状态本身与母乳喂养时间短无关。患有T1D的母亲母乳喂养持续时间较短的主要原因是她们的剖腹产频率更高,分娩更早,年龄和文化程度较低。

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