One-year efficacy and safety of a fixed combination of insulin degludec and liraglutide in patients with type 2 diabetes: results of a 26-week extension to a 26-week main trial

Gough S. C. L.; Bode B. W.; Woo V. C.; Rodbard H. W.; Linjawi S.; Zacho M.; Reiter P. D.; Buse J. B.

首页> 外文期刊>Diabetes, obesity & metabolism >One-year efficacy and safety of a fixed combination of insulin degludec and liraglutide in patients with type 2 diabetes: results of a 26-week extension to a 26-week main trial

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One-year efficacy and safety of a fixed combination of insulin degludec and liraglutide in patients with type 2 diabetes: results of a 26-week extension to a 26-week main trial

机译：地格列克胰岛素和利拉鲁肽固定组合对2型糖尿病患者的一年疗效和安全性：将26周延长至26周主要试验的结果

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Aims: To confirm, in a 26-week extension study, the sustained efficacy and safety of a fixed combination of insulin degludec and liraglutide (IDegLira) compared with either insulin degludec or liraglutide alone, in patients with type 2 diabetes.

机译：目的：在一项为期26周的扩展研究中，证实2型糖尿病患者中，胰岛素德格列酯和利拉鲁肽固定组合（IDegLira）与单独使用胰岛素德格列酯或利拉鲁肽相比具有持续的疗效和安全性。

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《Diabetes, obesity & metabolism 》 |2015年第10期| 共9页
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Gough S. C. L.; Bode B. W.; Woo V. C.; Rodbard H. W.; Linjawi S.; Zacho M.; Reiter P. D.; Buse J. B.;
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正文语种 eng
中图分类内分泌腺疾病及代谢病 ;
关键词
diabetes therapy; hypoglycaemia; insulin degludec; liraglutide;

机译：糖尿病治疗;低血糖;脱地胰岛素;利拉鲁肽;

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1. One-year efficacy and safety of a fixed combination of insulin degludec and liraglutide in patients with type 2 diabetes: results of a 26-week extension to a 26-week main trial [J] . Gough S. C. L., Bode B. W., Woo V. C., Diabetes, obesity & metabolism . 2015 ,第10期

机译：地格列克胰岛素和利拉鲁肽固定组合对2型糖尿病患者的一年疗效和安全性：将26周延长至26周主要试验的结果
2. Superior efficacy with a fixed‐ratio combination of insulin degludec and liraglutide (IDegLira) compared with insulin degludec and liraglutide in insulin‐na?ve Japanese patients with type 2 diabetes in a phase 3, open‐label, randomized trial [J] . Kaku Kohei, Araki Eiichi, Tanizawa Yukio, Diabetes, obesity & metabolism . 2019 ,第12期

机译：与胰岛素Degludec和Liragludec和Liraglutide在胰岛素-Na've的胰岛素Degludec和Liraglutide中的胰岛素-Na've日本患者的胰岛素Degludec和Liraglutide的卓越疗效卓越的疗效与第3型糖尿病患者，开放标签，随机试验
3. The efficacy and safety of insulin degludec given in variable once-daily dosing intervals compared with insulin glargine and insulin degludec dosed at the same time daily: A 26-week, randomized, open-label, parallel-group, treat-to-target trial in individuals with type 2 diabetes [J] . MeneghiniL., AtkinS.L., GoughS.C.L., Diabetes care . 2013 ,第4期

机译：与每日一次同时给药的甘精胰岛素和地格列松胰岛素相比，以每天一次的可变给药间隔给予地格列松胰岛素的疗效和安全性：一项为期26周，随机，开放标签，平行组，以治疗为目标的试验在2型糖尿病患者中
4. Long-acting Insulin in Diabetes Therapy: In Silico Clinical Trials with the UVA/Padova Type 1 Diabetes Simulator^* [C] . Roberto Visentin, Michele Schiavon, Clemens Giegerich, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2018

机译：长效胰岛素在糖尿病治疗中的作用：采用UVA / Padova 1型糖尿病模拟器的Silico临床试验^*
5. Incidence of hypoglycemia and associated costs in Type 1and Type 2 diabetes patients treated with insulin analogs vs. human insulin: A retrospective cohort study. [D] . Shah, Hiren P. 2014

机译：使用胰岛素类似物与人胰岛素治疗的1型和2型糖尿病患者的低血糖发生率和相关费用：一项回顾性队列研究。
6. One‐year efficacy and safety of a fixed combination of insulin degludec and liraglutide in patients with type 2 diabetes: results of a 26‐week extension to a 26‐week main trial [O] . S. C. L. Gough, B. W. Bode, V. C. Woo, -1

机译：地格列克胰岛素和利拉鲁肽固定组合对2型糖尿病患者的一年疗效和安全性：将26周延长至26周主要试验的结果
7. One‐year efficacy and safety of a fixed combination of insulin degludec and liraglutide in patients with type 2 diabetes: results of a 26‐week extension to a 26‐week main trial [O] . S. C. L. Gough, B. W. Bode, V. C. Woo, 2015

机译：2型糖尿病患者胰岛素Degludec和Liraglutide的固定组合的一年疗效和安全性：26周主要试验的26周延长结果

One-year efficacy and safety of a fixed combination of insulin degludec and liraglutide in patients with type 2 diabetes: results of a 26-week extension to a 26-week main trial

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