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Odontoid Fractures With Neurologic Deficit Have Higher Mortality and Morbidity

机译:具有神经系统缺陷的齿突骨折的死亡率和发病率较高

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Background Type II odontoid fractures are reportedly increasing in incidence and occur primarily in the elderly. Neurologic deficits (ND) at presentation add to the morbidity of these fractures; however, reports are limited as a result of small case series. It is unclear what specific complications are associated with ND and whether these result in increased incidence of mortality.Questions/purposes We established the incidence of ND with Type II odontoid fractures and determined if ND are associated with increased inpatient mortality and morbidity during hospitalization.Methods Twenty patients with acute Type II odontoid fracture and ND were identified from our institutional database. Baseline presenting characteristics and hospital course data were collected. The cohort was compared with a previously published cohort of 188 patients without ND by age, mechanism of injury, displacement, associated spinal injuries, comorbidities, treatment, mortality, and complications. Patients were only followed during cute-care hospitalization (mean, 11.9 days; range, 0-41 days). Results The incidence of ND among all Type II odontoid fractures was 9.6%. Ten of 20 patients with Type II odontoid fractures and ND died during hospitalization, and patients with complete cord injuries were 9.33 (95% confidence interval, 1.19-73.0) times more likely to die. Patients with ND experienced more complications and more respiratory complications than those without ND. Conclusions ND after Type II odontoid fractures is a rare event associated with a high risk of early and rapid clinical decline.Level of Evidence Level m, prognostic study. See Guidelines for Authors for a complete description of levels of evidence.
机译:背景技术据报道,II型齿状突骨折的发病率正在增加,并且主要发生在老年人中。出现神经功能缺损(ND)会增加这些骨折的发病率。但是,由于案例数量少,报告数量有限。目前尚不清楚哪些特定并发症与ND相关,以及这些并发症是否导致死亡率增加。问题/目的我们确定了II型齿状突骨折的ND发病率,并确定ND是否与住院期间住院死亡率和发病率增加相关。从我们的机构数据库中识别出了20例急性II型齿状突骨折和ND患者。收集基线表现特征和医院病历数据。通过年龄,损伤机制,移位,相关脊柱损伤,合并症,治疗,死亡率和并发症,将该队列与先前发表的188例无ND的患者进行比较。仅在可爱护理住院期间(平均11.9天;范围0-41天)对患者进行随访。结果所有II型齿状突骨折中ND的发生率为9.6%。 20例II型齿状突骨折和ND的患者中有10例在住院期间死亡,而完全性脊髓损伤的患者死亡的可能性高9.33倍(95%置信区间,1.19-73.0)。 ND患者比无ND患者经历更多的并发症和更多的呼吸道并发症。结论II型齿状突骨折后的ND是罕见的事件,伴有早期和快速临床下降的高风险。证据水平m,预后研究。有关证据水平的完整说明,请参见《作者指南》。

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