Study on dietary habit and effect of onion powder supplementation on serum lipid levels in early diagnosed hyperlipidemic patients.

摘要

This study aimed to determine the effects of freeze-dried onion powder (OP) which is rich in quercetin (22 mg/10 g) on hyperlipidaemic subjects. 14 participants (total cholesterol level in plasma 270.8 +or- 21.4 mg/dl) 40-59 yr of age who were diagnosed with hyperlipidaemia by a physician at Fatima Hospital in Changwon took part in the study for 12 wk. Anthropometric data and dietary habits were determined using questionnaires. Blood samples were collected from the fasting patients before and after the study. 78.6% of the patients showed interest in diet management for health and wt. control; however, they also showed some problems in their dietary habits (meal irregularity, food choice, calorie nutrient balance, high fat and cholesterol, etc.) and life style (smoking, eating out, alcohol intake) that could have adverse effects on hyperlipidaemic therapy. Most participants (85.7%) thought that OP was good for their health. Total cholesterol and LDL-cholesterol significantly decreased with OP intake. HDL-cholesterol increased and the atherogenic index (AI) significantly decreased. Regarding the correlations of dietary habit and life style with anthropometric and biochemical factors, alcohol intake level was significantly correlated with the frequency of eating out and body mass index (BMI). Exercise level showed positive correlation with HDL-cholesterol and negative correlation with atherogenic index (AI). These results suggest that the intake of polyphenol rich onion may decrease the risk of hyperlipidaemia by reducing cholesterol level. The hypolipidaemic effects suggest that OP could be a possible functional food. However, further research, e.g. a well designed longterm clinical study with experimental and placebo groups, is needed.