An automatic warning system for epileptic seizures recorded on intracerebral EEGs.

摘要

OBJECTIVE: A new clinical seizure waning system for intracerebral EEG is proposed. It is aimed at a better performance than existing systems and at user tuneability. METHODS: The system employs data filtering in multiple bands, spectral feature extraction, Bayes' theorem, and spatio-temporal analysis. The a priori information in Bayes' theorem was provided by 407 h of EEG from 19 patients having 152 seizures. RESULTS: The testing data (19 patients, 389 h, 100 seizures, independent of the training data) yielded a sensitivity of 89.4%, a false detection rate of 0.22/h, and median delay time of 17.1 s when tuning was used, and 86%, 0.47/h and 16.2 s without tuning. Missed seizures were of short duration or had subtle seizure activity. False detections were caused by technical artefacts, non-epileptic large amplitude rhythmic bursts or very low amplitude activity. It was established that performance could easily be tuned. Results were also compared to the clinical system of . CONCLUSIONS: The system offersa performance that is acceptable for clinical use. User tuneability allows for reduction in false detection with minimal loss to sensitivity. SIGNIFICANCE: Epilepsy monitoring generates large amounts of recordings and requires intense observation. Automatic seizure detection and warning systems reduce review time and facilitate observation. We propose a method with high sensitivity and few false alarms.