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Not all systematic reviews are systematic: A meta-review of the quality of systematic reviews for non-invasive remote monitoring in heart failure

机译:并非所有的系统评价都具有系统性:对心力衰竭的无创远程监测系统评价的质量的元评价

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摘要

We carried out a critical appraisal and synthesis of the systematic reviews and meta-analyses of remote monitoring for heart failure. A comprehensive literature search identified 65 relevant publications from 3333 citations. Seventeen studies fulfilled the inclusion and exclusion criteria. Seven (41%) systematic reviews pooled results for meta-analysis. Eight (47%) considered all non-invasive remote monitoring strategies. Five (29%) focused on telemonitoring. Four (24%) included both non-invasive and invasive technologies. The reviews were appraised by two independent reviewers for their quality and risk of bias using the AMSTAR tool. According to the AMSTAR criteria, ten (58%) systematic reviews were of poor methodological quality. In the high quality reviews, the relative risk of mortality in patients who received remote monitoring ranged from 0.53 to 0.88. The high quality reviews also reported that remote monitoring reduced the relative risk of all-cause (0.52 to 0.96) and heart failure-related hospitalizations (0.72 to 0.79) and, as a consequence, healthcare costs. However, further research is required before considering widespread implementation of remote monitoring. The subset of the heart failure population that derives the most benefit from intensive monitoring, the best technology, and the optimum duration of monitoring, all need to be identified.
机译:我们对心力衰竭远程监测的系统评价和荟萃分析进行了严格的评估和综合。全面的文献搜索从3333篇文献中找到了65种相关出版物。十七项研究符合纳入和排除标准。七项(41%)系统评价汇总了结果以进行荟萃分析。八个(47%)考虑了所有非侵入式远程监控策略。五(29%)人专注于远程监控。四个(24%)包括非侵入式和侵入式技术。两名独立评审使用AMSTAR工具对评审的质量和偏见风险进行了评价。根据AMSTAR标准,十个(58%)系统评价的方法学质量较差。在高质量的评价中,接受远程监测的患者的相对死亡风险为0.53至0.88。高质量的评论还报告说,远程监测降低了全因和因心力衰竭而住院的相对风险(0.52至0.96),并因此降低了医疗费用。但是,在考虑广泛实施远程监控之前,需要进行进一步的研究。需要从集中监测,最佳技术和最佳监测持续时间中获得最大收益的心力衰竭人群的子集。

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