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For debate: The august sun and the december snow

机译:辩论:八月的太阳和十二月的雪

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A growing body of evidence claims there is a pivotal role of heat temperatures and summer hot spells in the pathogenesis of exceeding morbidity and mortality among older people. The European well-known " 2003 killer hot summer" has boosted many epidemiological and clinical investigations to clarify the pathogenetic correlation between hot spells and elderly mortality with new acquirements in terms of pathophysiology, preventive measures, and therapeutic approaches. However, a quite controversial issue arises: overall elderly mortality is higher in the cold winter compared with summer. The progressive development of preventive, therapeutic, and environmental measures, if targeted with promptness, has generally proven effective in coping with heat temperature, restraining elderly mortality.However, few investigations have been performed dealing with cold, with pioneeristic as well as simplistic approaches, without any conclusiveness or effectiveness in terms of prevention or therapy. Data from recent literature enlist various clinical and environmental approaches in counteracting cold-related mortality in elderly, but lack evidence-based results; a recent European collaborative study reported cold-related elderly mortality as non-negligible, deserving the growing attention of public authorities.We conducted a 4-year survey among 6 different nursing homes located in a seaside city of northern Italy so as to collect epidemiological data on stressful weather spells and elderly mortality. Our results showed that overall elderly mortality in the cold season displayed as significantly high rates as in summer, and the monthly deaths per year of observation showed higher rates in the cold season, addressing it as the most prevalent time period related to mortality in older people. Thus, research in the field is mandatory so as to draw a broader conceptual framework for the stratification of specific population risk profiling and the assessment of adequate preventive and therapeutic measures. To the present knowledge, the lack of pathophysiological understanding, the missing evidence-based data in coping with cold weather-related elderly mortality, together with policy makers' misconceptions is mounting the controversy on this emerging clinical issue.
机译:越来越多的证据表明,高温和夏季炎热在老年人发病率和死亡率超标的发病机理中起着关键作用。欧洲著名的“ 2003炎热夏季杀手”已经推动了许多流行病学和临床研究,以通过病理生理学,预防措施和治疗方法方面的新成果,阐明了炎热的发作与老年人死亡率之间的致病关系。然而,一个颇具争议的问题出现了:在寒冷的冬季,老年人的总体死亡率要高于夏季。预防性,治疗性和环境性措施的逐步发展,如果能迅速解决,通常被证明可以有效地应对高温,抑制老年人的死亡。但是,很少有关于感冒的研究,无论是开创性的还是简单的方法,在预防或治疗方面没有任何结论性或有效性。最新文献中的数据采用多种临床和环境方法来抵消老年人与感冒相关的死亡率,但缺乏循证医学结果。欧洲最近的一项合作研究报告说,与感冒相关的老年人死亡率不可忽略,值得公共当局日益重视。我们对位于意大利北部海滨城市的6家不同的养老院进行了为期4年的调查,以收集流行病学数据恶劣的天气和老年人的死亡率。我们的结果表明,寒冷季节的老年人总死亡率显示出与夏季相当高的比率,每年观察到的每月死亡表明寒冷季节的比率更高,这被认为是与老年人死亡率相关的最普遍的时期。因此,该领域的研究是必不可少的,以便为特定人群风险特征的分层以及评估适当的预防和治疗措施提供更广阔的概念框架。就目前的知识而言,缺乏对病理生理学的了解,缺乏与寒冷天气相关的老年人死亡率的循证数据,以及决策者的误解,使这一新出现的临床问题引起了争议。

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