Outcome of surgical versus medical treatment of dogs with beta cell neoplasia: 39 cases (1990-1997).

摘要

39 dogs with beta cell neoplasia were used to compare outcome of surgical versus conservative treatment. 26 dogs underwent exploratory celiotomy and partial pancreatectomy; 13 dogs were treated conservatively (i.e. dietary change and prednisone). Median survival time was significantly longer for dogs treated surgically than for dogs treated conservatively. There was no significant differences in mean age, body weight, duration of clinical signs before diagnosis, serum glucose and insulin concentration, or results of other serum biochemical tests between the two groups nor was there any correlation between these parameters and survival time for either group of dogs. It is suggested that exploratory celiotomy and partial pancreatectomy are indicatedonce a tentative diagnosis of beta cell neoplasia is established in dogs.