Sunlight-induced decarboxylative radical addition of carboxylic acids to electron-deficient alkenes using a millitube reactor

摘要

The use of a fluorinated ethylene propylene (FEP) millitube reactor significantly improved the efficiency of the photoinduced decarboxylative radical addition of aliphatic carboxylic acids to electron-deficient alkenes, producing the corresponding gamma-amino acid derivative and macrocyclic lactone. These sunlight-induced photoreactions were achieved using a millitube reactor, even though the photosensitizer used in this system absorbs only UV light. (C) 2016 Elsevier B.V. All rights reserved.