Synthesis of some new 5-substituted-3-phenyl-4-thioxo-2-thiazolidinones and their fused thiopyrano[2,3-d]thiazole derivatives

摘要

The new 5-arylmethylene-3-phenyl-4-thioxo-2-thiazolidinone derivatives have been synthesized by condensation of -(4-formylphenoxy)acetophenone derivatives with 3-phenyl-4-thioxo-2-thiazolidinone, in good yields. The cycloaddition of the newly synthesized compounds to N-arylmaleimides, ethyl acrylate and -nitrostyrene has been studied. Under thermal reaction conditions [4+2] cycloaddition proceeds with complete site- and regioselectivity to yield the new fused thiopyrano[2,3-d]thiazole derivatives.