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We wish to thank Dr Conijn and Drs Rice and Blackstone for their letters and for their interest in our work on the use of biologic mesh for paraesophageal hernias (PEH)* and for the opportunity to respond.Dr Conijn asked whether we analyzed the relationship between hernia recurrence and symptoms. We have, and it was the primary aim of our recently published paper.2 In that analysis, we found that patients with recurrent hernias ^4 cm experienced slightly greater heartburn than those with no recurrence, but there was no difference in all other symptoms. This confirmed our clinical suspicion that if a well-constructed fundoplication is added at the time of treatment of a PEH, a recurrence might result in some degree of gastroesophageal reflux, but is unlikely to lead to obstructive symptoms of the kind with which patients with PEHs often present.
机译:我们要感谢Conijn博士以及Rice和Blackstone博士的来信,以及他们对我们在使用生物网片治疗食管旁食道疝(PEH)*方面所做的工作的兴趣以及能够做出回应的机会.Conijn博士询问我们是否分析了两者之间的关系疝气复发和症状。我们已经做到了,这是我们最近发表的论文的主要目标。2在该分析中,我们发现复发性疝≥4 cm的患者比没有复发的患者经历的胃灼热略有增加,但是在所有其他症状上没有差异。这证实了我们的临床怀疑,即如果在治疗PEH时加上结构良好的胃底折叠术,复发可能会导致一定程度的胃食管反流,但不太可能导致PEHs患者出现阻塞性症状经常出现。

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