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首页> 外文期刊>Journal of the American College of Cardiology >Reply: Enalapril and carvedilol for preventing chemotherapy-induced left ventricular systolic dysfunction in patients with malignant hemopathies
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Reply: Enalapril and carvedilol for preventing chemotherapy-induced left ventricular systolic dysfunction in patients with malignant hemopathies

机译:回复:依那普利和卡维地洛预防恶性血液病患者化疗引起的左心室收缩功能障碍

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摘要

Since the last World Symposium on Pulmonary Hypertension in 2008, we have witnessed numerous and exciting developments in chronic thromboembolic pulmonary hypertension (CTEPH). Emerging clinical data and advances in technology have led to reinforcing and updated guidance on diagnostic approaches to pulmonary hypertension, guidelines that we hope will lead to better recognition and more timely diagnosis of CTEPH. We have new data on treatment practices across international boundaries as well as long-term outcomes for CTEPH patients treated with or without pulmonary endarterectomy. Furthermore, we have expanded data on alternative treatment options for select CTEPH patients, including data from multiple clinical trials of medical therapy, including 1 recent pivotal trial, and compelling case series of percutaneous pulmonary angioplasty. Lastly, we have garnered more experience, and on a larger international scale, with pulmonary endarterectomy, which is the treatment of choice for operable CTEPH. This report overviews and highlights these important interval developments as deliberated among our task force of CTEPH experts and presented at the 2013 World Symposium on Pulmonary Hypertension in Nice, France.
机译:自2008年上届世界肺动脉高压研讨会以来,我们目睹了慢性血栓栓塞性肺动脉高压(CTEPH)的众多令人振奋的发展。新兴的临床数据和技术进步已导致对肺动脉高压的诊断方法进行加强和更新的指导,我们希望这些指导能够导致对CTEPH的更好认识和更及时的诊断。我们获得了有关国际范围内的治疗实践以及接受或不接受肺动脉内膜切除术的CTEPH患者的长期结果的新数据。此外,我们扩展了针对某些CTEPH患者的替代治疗选择的数据,包括来自多项药物治疗的临床试验的数据,包括1项近期的关键性试验以及令人信服的经皮肺血管成形术病例系列。最后,我们在肺动脉内膜切除术方面获得了更多的经验,并且在更大的国际范围内,这是可手术的CTEPH的治疗选择。本报告概述并强调了这些重要的间歇发展,这些进展是由我们的CTEPH专家小组审议并在2013年法国尼斯召开的世界肺动脉高压研讨会上提出的。

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