Hydrophobic ionic liquid-based ultrasoundassisted extraction of magnolol and honokiol from cortex Magnoliae officinalis

摘要

The hydrophobic ionic liquid of [BMIM][PF_6] was successfully used for the ultrasound-assisted extraction of hydrophobic magnolol and honokiol from cortex Magnoliae officinalis. To obtain the best extraction efficiencies, some ultrasonic parameters including the concentration of [BMIM][PF _6], pH, ultrasonic power and ultrasonic time were evaluated. The results obtained indicated that the [BMIM][PF_6]-based ultrasound-assisted extraction efficiencies of magnolol and honokiol were greater than those of the [BMIM][BF_4]-based ultrasound-assisted extraction (from 48.6 to 45.9%) and the traditional ethanol reflux extraction (from 16.2 to 13.3%). Furthermore, the proposed extraction method is validated by the recovery, correlation coefficient (R~2) and reproducibility (RSD, n=5), which were 90.8-102.6, 0.9992-0.9998, and 1.6-5.4%, respectively.