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Regulating exposure of the lens of the eye to ionising radiations

机译:调节眼睛晶状体对电离辐射的暴露

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摘要

The International Commission on Radiological Protection (ICRP) has reviewed recent epidemiological evidence suggesting that, for the lens of the eye, the threshold in absorbed dose for the induction of deleterious health effects is about 0.5Gy. On this basis, the Commission recommends that for occupational exposure in planned exposure situations, the equivalent dose limit for the lens of the eye should be 20mSv in a year, averaged over defined periods of 5yr, with exposure not exceeding 50mSv in any single year. This paper summarises the data that have been taken into account by the ICRP and critically examines whether the proposed downward revision of the dose limit is justified. Overall, it is concluded that the accumulating radiobiological and epidemiological evidence makes it more appropriate to treat cataract induction as a stochastic rather than a deterministic effect. Within this framework, it is illogical to have the same dose limit for the lens of the eye as for the whole body irradiated uniformly. This could be addressed either by removing the special dose limit for the lens of the eye, assigning it an appropriate tissue weighting factor and including it in the computation of the effective dose, or through a composite approach involving the use of a tissue weighting factor for effective dose computations together with a special limit on the equivalent dose to the lens of the eye to ensure that no individual was subject to an unacceptably high risk of induction of clinically significant cataracts.
机译:国际放射防护委员会(ICRP)审查了最近的流行病学证据,这些证据表明,对于眼睛的晶状体,诱导有害健康影响的吸收剂量阈值约为0.5Gy。在此基础上,委员会建议,对于计划中的暴露情况下的职业暴露,每年晶状体的等效剂量限值应为每年20mSv,在定义的5年内平均,任何一年的暴露量均不得超过50mSv。本文总结了ICRP所考虑的数据,并严格审查了建议的剂量限值下调是否合理。总体而言,得出的结论是,放射生物学和流行病学证据的积累使将白内障诱导视为随机效应而非确定性效应更为合适。在此框架内,对眼睛的晶状体使用与均匀照射的整个身体相同的剂量限制是不合逻辑的。可以通过以下方法解决此问题:删除眼晶状体的特殊剂量限制,为其分配适当的组织权重因子,并将其包括在有效剂量的计算中,或者通过涉及使用组织权重因子的复合方法来解决。有效的剂量计算以及对眼睛晶状体等效剂量的特殊限制,以确保没有任何个体遭受诱发具有临床意义的白内障的高风险。

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