Management of central giant cell granuloma of mandible using intralesional corticosteroids: case report and review of literature.

摘要

The World Health Organization has defined central giant cell granuloma (CGCG) as "an intraosseous lesion consisting of cellular fibrous tissue containing multiple foci of hemorrhage, aggregations of multinu-cleated giant cells, and occasionally, trabeculae of woven bone."1 The lesion was first described in 1953 by Jaffe and termed a giant cell reparative granuloma.1'2 He further opined that these lesions were not true neoplasms but, rather, represented a local reparative reaction.3 Subsequent experience revealed that the clinical behavior of the lesion is largely inconsistent with a reparative process, and the term "reparative" was dropped.1 Currently, and despite the current World Health Organization definition, the true nature of the lesion is unknown.