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Stent-assisted coil embolization of ruptured wide-necked aneurysms in the acute period: Incidence of and risk factors for periprocedural complications: Clinical article

机译:急性期宽颈动脉瘤的支架辅助线圈栓塞术:围手术期并发症的发生率和危险因素:临床文章

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Object. The purpose of this study was to report the authors' experiences in stent-assisted coil embolization (SAC) of ruptured wide-necked aneurysms in the acute period and to evaluate the incidence of and risk factors for periprocedural complications. Methods. A total of 72 patients were recruited for this study between March 2007 and June 2012. All patients met the following criteria: 1) the presence of ruptured intracranial wide-necked saccular aneurysms, and 2) the patient underwent SAC for treatment of those aneurysms within 72 hours of rupture. All of the patients with clinically poor grades or acute hydrocephalus underwent external ventricular drainage (EVD) before SAC. The incidence of and risk factors for periprocedural complications were retrospectively evaluated. Results. Of the 72 patients included in this study, periprocedural complications occurred in 14 (19.4%), including asymptomatic complications in 4 (5.6%) and symptomatic complications in 10 (13.9%); there were symptomatic thromboembolic complications in 5 patients (6.9%), and symptomatic hemorrhagic complications in 5 (6.9%). The authors observed no subacute or delayed thromboembolic complications during the follow-up period of 18.8 months. Use of EVD (OR 1.413, 95% CI 0.088-2.173; p = 0.046) was the only independent risk factor for periprocedural complications on multivariate logistic regression analysis. Conclusions. The periprocedural complication rate during SAC was 19.4% among 72 patients. Because of the high complication rate, microsurgical clipping or endovascular treatment with another technique (multiple-microcatheter or balloon-assisted technique) may be a more appropriate option for first-line treatment than SAC, especially in patients requiring EVD.
机译:目的。本研究的目的是报告作者在急性期破裂性广颈动脉瘤的支架辅助线圈栓塞(SAC)中的经验,并评估围手术期并发症的发生率和危险因素。方法。在2007年3月至2012年6月之间,共招募了72位患者参加该研究。所有患者均符合以下标准:1)颅内宽颈囊状动脉瘤破裂,2)该患者接受SAC治疗以治疗这些动脉瘤破裂72小时。在SAC之前,所有临床评分不佳或急性脑积水的患者均接受了外部心室引流(EVD)。回顾性评估围手术期并发症的发生率和危险因素。结果。在该研究的72例患者中,有14例(19.4%)发生了围手术期并发症,其中无症状并发症4例(5.6%)和有症状并发症10例(13.9%);有症状的血栓栓塞并发症5例(6.9%),有症状的出血并发症5例(6.9%)。作者在18.8个月的随访期间未观察到亚急性或延迟性血栓栓塞并发症。在多因素logistic回归分析中,使用EVD(OR 1.413,95%CI 0.088-2.173; p = 0.046)是围手术期并发症的唯一独立危险因素。结论。 SAC期间围手术期并发症发生率在72例患者中为19.4%。由于并发症的发生率高,因此与SAC相比,显微外科钳夹或采用另一种技术(多微导管或球囊辅助技术)进行血管内治疗可能是更适合一线治疗的选择,尤其是在需要EVD的患者中。

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