Re: Diagnostic performance of PWI/DWI MRI parameters in discriminating hyper-acute versus acute ischaemic stroke: Finding the best thresholds

摘要

I read with interest the paper by Roldan-Valadez et al. recently published in this Journal. The study focused on the discriminating ability of several magnetic resonance imaging (MRI) parameters for hyper-acute ischaemic stroke in 25 male and 30 female patients. Based on receiver operating characteristics (ROC) analysis and logistic regression analysis, it was revealed that hyper-acute ischaemic stroke can only be diagnosed by time to peak (TTP) >3 s. The target subjects were limited to patients with hyper-acute (first 6 h) and acute (7-24 h) stroke, and assessment was conducted to identify the patients with hyper-acute ischaemic stroke among the study participants.