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An assessment of selective cerebral perfusion via the innominate artery in aortic arch replacement.

机译:通过主动脉弓置换术中的无名动脉进行选择性脑灌注的评估。

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Maintaining an adequate cerebral oxygen supply is a serious problem in aortic arch surgery. Deep hypothermic circulatory arrest is the most common method used for cerebral protection, but guarantees only a time-limited safety period. Based on experimental investigations, we applied selective cerebral perfusion via the innominate artery alone with only moderate hypothermia (28 degrees C) and without circulatory arrest in 25 consecutive patients undergoing surgical treatment of an aneurysm (n = 10) or acute type-A dissection (n = 15) involving the aortic valve and arch. In every case a test perfusion was carried out to assess whether the cerebral perfusion achieved would be adequate for the whole operation. In no case was the perfusion inadequate. As a new perioperative monitoring system, we used computer-aided topographical electroencephalometry (CATEEM). There were 18 male and 7 female patients, their age was 47.0 +/- 15.1 years (mean +/- SD). Mean time periods were 155.1 +/- 37.3 min for aortic cross-clamping, and 69.3 +/- 35 min for selective cerebral perfusion. Postoperatively, two patients (8%) revealed a temporary left-sided hemiparesis, and 4 patients (16%) died within 30 days. The overall mortality rate was 16% in a follow-up period of 24.2 +/- 9.5 months. In this small group the CATEEM monitoring enabled an intraoperative selection of patients with sufficient bihemispheric collateral circulation and therefore suitable for simple innominate artery perfusion.
机译:在主动脉弓手术中,维持充足的脑氧供应是一个严重的问题。低温低温循环止动是用于脑保护的最常用方法,但只能保证有时间限制的安全期。根据实验研究,我们对25例接受动脉瘤手术(n = 10)或急性A型夹层手术治疗的连续患者进行了选择性脑灌注,仅通过中度低温(28°C)而无循环停止。 n = 15)涉及主动脉瓣和弓。在每种情况下都进行了测试灌注,以评估获得的脑灌注是否适合整个手术。在任何情况下,灌注都不会不足。作为一种新的围手术期监测系统,我们使用了计算机辅助地形图脑电图(CATEEM)。男18例,女7例,年龄47.0 +/- 15.1岁(平均+/- SD)。主动脉钳夹的平均时间为155.1 +/- 37.3分钟,选择性脑灌注的平均时间为69.3 +/- 35分钟。术后有2例患者(8%)出现暂时性左侧偏瘫,4例患者(16%)在30天内死亡。在24.2 +/- 9.5个月的随访期内,总死亡率为16%。在这一小组中,CATEEM监测可在术中选择具有足够双半球侧支循环的患者,因此适合进行简单的无名动脉灌注。

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