Reduction of glucose metabolism in basal ganglia diagnosed with FDG-PET scan: a neuroacanthocytosis case.

摘要

Neuroacanthocytosis is a rare movement disorder marked by progressive muscle weakness and atrophy, progressive cognitive loss, chorea, and acanthocytosis. Neuroacanthocytosis is typically an inherited autosomal recessive disorder and is more common in males than in females. The disorder is due to degeneration of the basal ganglia by loss of neurons. Symptoms typically occur between 25 and 45 years of age. FDG PET has been increasingly used for detection of neurologic disorders, such as dementia, epilepsy, and movement disorders. We present an interesting case of neuroacanthocytosis with FDG-PET images showing decreased FDG uptake in the basal ganglia.