A new voltammetric sensor based on poly(L-arginine)/graphene-Nafion composite film modified electrode for sensitive determination of Terbutaline sulfate

摘要

A novel voltammetric sensor based on graphene-Nafion and poly(L-arginine) was constructed by electrodeposited and simple dipping-drying methods and used for high-sensitive determination of Terbutaline sulfate (TBS). The resulting poly(L-arginine)/graphene-Nafion modified electrode showed a significant voltammetric response to TBS due to the synergistic effect of poly(L-arginine) and graphene-Nafion, in which poly(L-arginine) had electrocatalytic ability for TBS and graphene provided a large specific surface area, excellent electric conductivity and electrocatalytic activity. The sensor gave a good linear range over 4.0x10~(-8)-5.0x10~(-6) mol L~(-1) with a detection limit of 1.2x10~(-8) mol L~(-1) towards the determination of TBS. The high sensitivity and selectivity together with the good linear relationship, very easy surface regeneration and good stability at such a modified electrode led us to construct a practical TBS biosensor successfully. This work promoted the potential applications of graphene-based materials in electrochemical sensors.