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Symptomatic duodenal Crohn's disease: Is strictureplasty the right choice?

机译:有症状的十二指肠克罗恩氏病:狭窄成形术是正确的选择吗?

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Primary duodenal localization of Crohn's disease (CD) is rare. Medical therapy can control symptoms, but surgery is required when progressive obstructive symptoms occur. Surgical options include bypass, resection, or strictureplasty, but it is still not clear which should be the treatment of choice. Reviewing the medical records of 1253 patients undergoing surgery for CD between January 1986 and December 2011 at the Digestive Surgery Unit of the Department of Clinical Physiopathology of the University of Florence, 10 patients (6 males and 4 females) underwent operations for duodenal CD. Four patients had only a duodenal localization, 6 patients had synchronous involvement of other intestinal tracts. Strictures were distributed in all the duodenal portions: in 7 patients there were single lesions, in 3 patients there were multiple lesions. Eight patients were treated with strictureplasty: 5 with the Heineke-Mikulicz technique, 2 with Jaboulay, and 1 with a pedunculated jejunal patch. Two patients were treated with resection: one with a B2 gastro-duodenal resection, and 1 with a duodenal-jejunal resection and an end to side duodeno-jejunal anastomosis. Follow up of the patients was from 2 to 18. years. No recurrence of duodenal CD was observed in the 2 patients treated with resection, while 2 of the 8 patients treated with strictureplasty had a recurrence. In our experience, strictureplasty is indicated when less than 2 strictures are present in the 2nd or 3rd duodenal portion. In cases with multiple strictures localized in the 1st or the distal duodenal portion, resection is preferable.
机译:克罗恩病(CD)的十二指肠原位定位很少。药物治疗可以控制症状,但是当发生进行性阻塞症状时需要手术。手术选择包括旁路,切除或狭窄成形术,但仍不清楚哪种治疗方法尚不明确。回顾了1986年1月至2011年12月在佛罗伦萨大学临床生理病理学系消化外科的1253例CD手术患者的病历,其中10例患者(男6例,女4例)接受了十二指肠CD手术。 4例患者仅有十二指肠定位,6例患者同时累及其他肠道。十二指肠的所有部位均分布有狭窄的部位:7例为单个病变,3例为多个病变。 8例患者接受了狭窄手术治疗:5例采用Heineke-Mikulicz技术,2例采用Jaboulay,1例采用带蒂空肠贴片。两名患者接受了切除术治疗:一名接受B2胃十二指肠切除术,一名接受十二指肠-空肠切除术并端对侧十二指肠-空肠吻合术。对患者的随访时间为2至18年。在接受切除的2例患者中未观察到十二指肠CD的复发,而接受狭窄成形术的8例患者中有2例复发。根据我们的经验,当十二指肠第二或第三部分少于2个狭窄时,即表示狭窄成形术。如果在第一或十二指肠远端部分有多个狭窄,则最好切除。

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