GAS-LIQUID CHROMATOGRAPHY MASS SPECTROMETRY OF PRIMARY AND SECONDARY FATTY ALCOHOLS AND DIOLS AS THEIR TERT.-BUTYLDIMETHYLSILYL DERIVATIVES

摘要

The use of gas-liquid chromatography (GLC) and mass spectrometry (MS) with derivatizing agents which give stable derivatives and informative fragmentation patterns allows for accurate identification of a variety of compounds. In this comprehensive study, the tert.-butyldimethylsilyl (tBDMS) derivatives of saturated and unsaturated primary alcohols, iso and anteiso-primary alcohols, branched alcohols, secondary alcohols and primary diols were produced and analyzed by GLC-MS. Most derivatized alcohols produced prominent mass minus 57 [M-57](+) fragment ions, which, combined with their respective retention data and other key fragment ions, allows for their identification and analysis.