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首页> 外文期刊>Journal of Clinical Pharmacy and Therapeutics >Age-related changes in consultations and antibiotic prescribing for acute respiratory infections, 1995-2000. Data from the UK General Practice Research Database.
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Age-related changes in consultations and antibiotic prescribing for acute respiratory infections, 1995-2000. Data from the UK General Practice Research Database.

机译:1995-2000年,与年龄有关的咨询和抗生素处方改变,用于急性呼吸道感染。数据来自英国全科医学研究数据库。

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Background: International studies using data aggregated for all ages have shown decreasing rates of general practice consultations for acute respiratory infections with fewer antibiotic prescriptions issued per consultation. The occurrence of different respiratory infections varies widely at different ages but we do not know whether prescribing has reduced equally in all age groups. Objective: We aimed to determine how reductions in consultation rates and antibiotic prescribing varied with age for different respiratory infections. Methods: Data were abstracted from the General Practice Research Database for 108 general practices in the UK (mean registered population 642 685). We estimated age-specific changes between 1995 and 2000 in consultation rates, and the proportion of consultations resulting in an antibiotic prescription for 'all respiratory infections' and for 'sore throat', 'ear infection', 'bronchitis' and 'chest infection'. Results: Consultation rates for 'all respiratory infections' declined in all age groups with the greatest decreases in children aged 1-4 years (41%), 5-10 year olds (53%) and 11-16 year olds (54%), whereas at 75-84 years the reduction was 28%. The pattern of greater reductions in children held for each separate condition even though the age of peak incidence varied. The relative reduction in antibiotic prescribing was greatest at 1-4 years (18%), 5-10 years (17%) and 11-16 years (17%), compared with 5% at 75-84 years. Antibiotic prescribing decreased most for sore throat and this was observed at all ages particularly in 5-10 year olds (relative reduction, 32%). Conclusions: School age children account for the greatest reduction in consultations for acute respiratory infection. School age and preschool children account for the greatest reductions in antibiotic prescribing during the consultation. The rapid changes in consultation rates are unexplained.
机译:背景:国际研究使用了所有年龄段的汇总数据,显示针对急性呼吸道感染的全科诊治率正在下降,每次诊治所开具的抗生素处方较少。不同年龄段不同呼吸道感染的发生率差异很大,但我们不知道处方是否在所有年龄段均得到同等减少。目的:我们旨在确定针对不同呼吸道感染的咨询率和抗生素处方的减少量如何随年龄而变化。方法:从英国的108个常规实践的通用实践研究数据库中提取数据(平均注册人口642685)。我们估计了1995年至2000年之间的特定年龄变化的咨询率,以及针对“所有呼吸道感染”和“咽喉痛”,“耳部感染”,“支气管炎”和“胸部感染”的抗生素处方的咨询比例。结果:所有年龄段的“所有呼吸道感染”咨询率均下降,其中1-4岁儿童(41%),5-10岁儿童(53%)和11-16岁儿童(54%)的下降幅度最大。 ,而在75-84岁时减少了28%。即使发生高峰的年龄各不相同,每种单独情况下儿童的减少幅度仍较大。抗生素处方的相对减少最大,分别为1-4年(18%),5-10年(17%)和11-16年(17%),而75-84年为5%。喉咙痛的抗生素处方减少最多,在所有年龄段都观察到,尤其是在5至10岁的人群中(相对减少32%)。结论:学龄儿童在急性呼吸道感染咨询中的减少最大。在咨询期间,学龄和学龄前儿童减少了抗生素处方的最大减少。咨询率的快速变化无法解释。

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