A dramatic story of hope and reality.

摘要

In the late 1980s and early 1990s, high-dose chemotherapy and autologous stem-cell transplantation seemed to be so promising for patients with metastatic breast cancer. Advanced breast cancer was a devastating disease with limited treatment options, Though responses were frequent, long-term remissions were generally uncommon, and median survival was perceived to be short. Conventional-dose chemotherapy and radiation therapy were inadequate and surgery of limited practicality.