Identification and analysis of anti-HDL scFv-antibodies obtained from phage display based synthetic antibody library

Negi Priyanka; Lovgren Janita; Malmi Paivi; Sirkka Nina; Metso Jari; Huovinen Tuomas; Brockmann Eeva-Christine; Pettersson Kim; Jauhiainen Matti; Lamminmaki Urpo

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Identification and analysis of anti-HDL scFv-antibodies obtained from phage display based synthetic antibody library

机译：从基于噬菌体展示的合成抗体库获得的抗HDL scFv抗体的鉴定和分析

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Objective: In epidemiological studies plasma high density lipoprotein cholesterol (HDL-C) levels are found to correlate inversely with atherosclerotic cardiovascular events. HDL consists of different subpopulations and they vary in their anti-atherogenic properties. The aim of this study is to isolate coronary artery disease (CAD) specific anti-HDL scFv-antibodies.

机译：目的：在流行病学研究中，血浆高密度脂蛋白胆固醇（HDL-C）水平与动脉粥样硬化性心血管事件呈负相关。 HDL由不同的亚群组成，它们的抗动脉粥样硬化特性也有所不同。这项研究的目的是分离冠状动脉疾病（CAD）特异性抗HDL scFv抗体。

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《Clinical Biochemistry》 |2016年第6期|共8页
作者
Negi Priyanka; Lovgren Janita; Malmi Paivi; Sirkka Nina; Metso Jari; Huovinen Tuomas; Brockmann Eeva-Christine; Pettersson Kim; Jauhiainen Matti; Lamminmaki Urpo;
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正文语种 eng
中图分类诊断学;
关键词
CAD; HDL; Lipoproteins; Apolipoproteins; Diagnostic tools; ApoA-I; ApoA-II;

机译：CAD;HDL;脂蛋白;载脂蛋白;诊断工具;ApoA-I;ApoA-II;

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1. Identification and analysis of anti-HDL scFv-antibodies obtained from phage display based synthetic antibody library [J] . Negi Priyanka, Lovgren Janita, Malmi Paivi, Clinical Biochemistry . 2016,第6期

机译：从基于噬菌体展示的合成抗体库获得的抗HDL scFv抗体的鉴定和分析
2. COMPREHENSIVE EPITOPE ANALYSIS OF MONOCLONAL ANTI-PROENKEPHALIN ANTIBODIES USING PHAGE DISPLAY LIBRARIES AND SYNTHETIC PEPTIDES - REVELATION OF ANTIBODY FINE SPECIFICITIES CAUSED BY SOMATIC MUTATIONS IN THE VARIABLE REGION GENES [J] . Bottger V., Lane EB., Spruce BA., Journal of Molecular Biology . 1995,第5期

机译：利用噬菌体展示库和合成肽对单克隆抗原脑啡肽抗体进行全面表位分析-可变区基因中体细胞突变引起的抗体精细特异性的揭示
3. Identification and Repair of Positive Binding Antibodies Containing Randomly Generated Amber Codons from Synthetic Phage Display Libraries [J] . Warren D.Marcus, Stuart M.Lindsay, Michael R.Sierks Biotechnology Progress . 2006,第3期

机译：从合成噬菌体展示文库鉴定和修复包含随机生成的琥珀密码子的阳性结合抗体
4. High Throughput Cytotoxicity Screening of Anti-HER2 Immunotoxins Conjugated with Antibody Fragments from Phage-Displayed Synthetic Antibody Libraries [C] . Hong-Sen Chen, Shin-Chen Hou, Hung-Wei Lin, PEGS . 2016

机译：与噬菌体展示合成抗体文库的抗体片段缀合的抗HER2免疫毒素的高通量细胞毒性筛选
5. Applications of phage-displayed antibody library for antibody discovery and engineering. [D] . Zhao, Qi. 2008

机译：噬菌体展示抗体库在抗体发现和工程设计中的应用。
6. High throughput discovery of influenza virus neutralizing antibodies from phage-displayed synthetic antibody libraries [O] . Ing-Chien Chen, Yi-Kai Chiu, Chung-Ming Yu, -1

机译：从噬菌体展示的合成抗体库中高通量发现流感病毒中和抗体
7. Identification and Repair of Positive Binding Antibodies Containing Randomly Generated Amber Codons from Synthetic Phage Display Libraries [O] . Warren D. Marcus, Stuart M. Lindsay, Michael R. Sierks 2015

机译：从合成噬菌体展示文库中鉴定和修复含有随机产生的琥珀密码子的阳性结合抗体
8. Identification of Novel Breast Cancer Antigens Using Phage Antibody Libraries. [R] . Marks, J. D. 2002

机译：用噬菌体抗体库鉴定新型乳腺癌抗原。

Identification and analysis of anti-HDL scFv-antibodies obtained from phage display based synthetic antibody library

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