Multi-component reaction between cyclohexyl isocyanide, cyanoacetic acid and aldehyde: Synthesis of methyl 2-cyano-3-(aryl)-cyclohexylcarbamoyl-(aryl)- acrylate

Anary-Abbasinejad M.; Hassanabadi A.; Kaldareh M.F.

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Multi-component reaction between cyclohexyl isocyanide, cyanoacetic acid and aldehyde: Synthesis of methyl 2-cyano-3-(aryl)-cyclohexylcarbamoyl-(aryl)- acrylate

机译：环己基异氰化物，氰基乙酸和醛之间的多组分反应：2-氰基-3-（芳基）-环己基氨基甲酰基-（芳基）-丙烯酸甲酯的合成

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An improved multi-component reaction of cyclohexyl isocyanide is described. The reaction between two equivalents of an aldehydes, cyclohexyl isocyanide and cyanoacetic acid at room temperature leads to methyl 2-cyano-3-(aryl)- cyclohexylcarbamoyl-(aryl)-acrylate in good yields.

机译：描述了环己基异氰化物的改进的多组分反应。在室温下，两个当量的醛，环己基异氰化物和氰基乙酸之间的反应以良好的收率得到2-氰基-3-（芳基）-环己基氨基甲酰基-（芳基）丙烯酸甲酯。

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《Journal of chemical research: reviews and research papers from all branches of chemistry》 |2010年第9期|共2页
作者
Anary-Abbasinejad M.; Hassanabadi A.; Kaldareh M.F.;
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正文语种 eng
中图分类化学;
关键词
Aldehydes; Cyanoacetic acid; Cyclohexyl isocyanide; Multi-component reaction;

机译：醛;氰乙酸;环己基异氰化物;多组分反应;

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1. Multi-component reaction between cyclohexyl isocyanide, cyanoacetic acid and aldehyde: Synthesis of methyl 2-cyano-3-(aryl)-cyclohexylcarbamoyl-(aryl)- acrylate [J] . Anary-Abbasinejad M., Hassanabadi A., Kaldareh M.F. Journal of chemical research: reviews and research papers from all branches of chemistry . 2010,第9期

机译：环己基异氰化物，氰基乙酸和醛之间的多组分反应：2-氰基-3-（芳基）-环己基氨基甲酰基-（芳基）-丙烯酸甲酯的合成
2. Synthesis of dialkyl {(aryl)[2,2-dimethyl-4-oxo-6-(piperidin-1-yl)-4H-[1,3] dioxin-5-yl]methyl}phosphonate by reaction of Meldrum's acid, aryl aldehydes and trialkyl phosphites in the presence of piperidine [J] . Khosravi R., Hosseini-Tabatabaei M.R., Forghaniha A. Journal of chemical research: reviews and research papers from all branches of chemistry . 2013,第7期

机译：麦德鲁姆酸反应合成{（芳基）[2,2-二甲基-4-氧代-6-（哌啶-1-基）-4H- [1,3]二恶英-5-基]甲基}膦酸二烷基酯，哌啶存在下的芳基醛和亚磷酸三烷基酯
3. Electrogenerated base promoted synthesis of 3-methyl-4-aryl-2,4,5,7-tetrahydropyrazolo[3,4-b]pyridin-6-ones via multicomponent reactions of 5-methylpyrazol-3-amine, aldehydes, and Meldrum's acid [J] . Veisi Hojat, Maleki Abbas, Jahangard Simin Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2015,第14期

机译：电生成的碱促进了5-甲基吡唑-3-胺，醛和梅德鲁姆氏反应的多组分反应，合成了3-甲基-4-芳基-2,4,5,7-四氢吡唑并[3,4-b]吡啶-6-酸
4. Ruthenocenyl Phosphine Designed as Novel Class of Phosphine-Arene Ligand: Application to Suzuki-Miyaura Reaction of Electronically and Sterically Deactivated Aryl Halides with Aryl Boronic Acids [C] . Takashi Hoshi, Taichi Nakazawa, Toshio Suzuki Symposium on Organometallic Chemistry . 2006

机译：设计为新型膦 - 芳烃配体的钌烯基膦：用芳族硼酸的电子和空间去激活的芳基卤化物的铃木 - 咪糕的反应应用
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机译：第一部分：使用钛催化剂的苯乙酮不对称氢化硅烷化。第二部分水溶性palladacycles的合成及其在铃木反应中的应用。第三部分铑催化的芳基和烯基硼酸加成醛
6. Aryl Ketone Synthesis via Tandem Orthoplatinated Triarylphosphite-Catalyzed Addition Reactions of Arylboronic Acids with Aldehydes Followed by Oxidation [O] . Yuan-Xi Liao, Qiao-Sheng Hu -1

机译：通过芳基硼酸与醛的串联Orthoplatinated三芳基亚磷酸酯催化加成反应的芳基酮的合成之后进行氧化
7. Synthesis of di-, tri-, and tetrasubstituted pyridines from (phenylthio)carboxylic acids and 2-[aryl(tosylimino)methyl]acrylates [O] . Stark, Daniel Graham, O’Riordan, Timothy J. C., Smith, Andrew David 2014

机译：由（苯硫基）羧酸和2- [芳基（甲苯基脲基）甲基]丙烯酸酯合成二，三和四取代的吡啶

Multi-component reaction between cyclohexyl isocyanide, cyanoacetic acid and aldehyde: Synthesis of methyl 2-cyano-3-(aryl)-cyclohexylcarbamoyl-(aryl)- acrylate

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