A high-throughput method for screening the moisture vapor transmission rate of barrier films was developed. This moisture high-throughput screening (MHTS) technique is based upon a Nafion-crystal violet (CVN) sensor that changes color from yellow to green upon absorption of water. Using an appropriate set of known standards, the slope of absorbance (at 630 nm) as a function of time can be converted into moisture vapor transmission rate (MVTR) values that agree with those obtained using ASTM F1290. High-throughput screening was demonstrated by depositing 20 emulsion-based poly (vinylidene chloride) films, using a 48-well template, of varying thicknesses onto the CVN sensor film and aging at 40 ℃ and 90% relative humidity for 72 h. MVTR values were accurately determined to a level of 0.9 g/m~2·day, at which point side-diffusion of moisture between the barrier and sensor films prevented observation of lower values. Larger sample size and edge-sealing are two proposed methods for improving the sensitivity of MHTS.
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机译：建立了一种高通量的屏障膜透湿率筛选方法。这种水分高通量筛选（MHTS）技术基于Nafion结晶紫（CVN）传感器，该传感器在吸水后从黄色变为绿色。使用适当的一组已知标准，可以将吸光度（在630 nm处）随时间的变化转换为与使用ASTM F1290获得的值一致的水蒸气透过率（MVTR）值。高通量筛选是通过使用48孔模板在CVN传感器膜上沉积20层不同厚度的乳液基聚（偏二氯乙烯）膜并在40℃和90％相对湿度下老化72 h来证明的。 MVTR值被精确地确定为0.9 g / m〜2·day，在这一点上，屏障和传感器膜之间的水分侧扩散阻止了较低值的观察。较大的样本量和边缘密封是提高MHTS灵敏度的两种建议方法。
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