Microwave-Enhanced Efficient Synthesis of Diversified 3,6-Disubstituted Pyridazines

摘要

Pyridazines have demonstrated versatile biological activities,for example,antibacterial,antidepressant,antihyper-tensive,analgesic,nephrotropic,antiinflammatory,anticancer,cardiotonic,antiaggregative,and inhibitory activities of acetylcholinesterase,aldose reductase,MAO,alpha_1-adrenoceptor,CDKs,COX-2,and p38 MAP kinase.