Single-Step Multisyntheses of Glycosyl Acceptors:Benzylation of n-1 Hydroxyl Groups of Phenylthio Glycosides of Xylose,Mannose, Glucose,Galactose, 2-Azido-2-deoxy-glucose, and 2-Azido-2-deoxy-galactose

摘要

An array of synthons is required to access an oligosaccharide library; however, multistep and thus time-consuming synthesis is inevitable. To rapidly access such synthetic units, multiple benzylation reactions of monosaccharides under phase-transfer conditions were examined. Multiple benzyl groups were successfully incorporated in one step, especially in the cases of reactions with triol systems.