Impact of chronic use of cibenzoline on left ventricular pressure gradient and left ventricular remodeling in patients with hypertrophic obstructive cardiomyopathy

Hamada Mareomi; Ikeda Shuntaro; Ohshima Kiyotaka; Nakamura Masayuki; Kubota Norio; Ogimoto Akiyoshi; Shigematsu Yuji

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Impact of chronic use of cibenzoline on left ventricular pressure gradient and left ventricular remodeling in patients with hypertrophic obstructive cardiomyopathy

机译：长期使用cibenzoline对肥厚性梗阻性心肌病患者左心室压力梯度和左心室重构的影响

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摘要

Background: Cibenzoline, a class Ia antiarrhythmic drug, is useful for reducing the left ventricular pressure gradient (LVPG) in patients with hypertrophic obstructive cardiomyopathy (HOCM). However, chronic effects of cibenzoline on LVPG and left ventricular (LV) remodeling are unknown.

机译：背景：Cibenzoline是Ia类抗心律不齐药物，可用于降低肥厚性梗阻性心肌病（HOCM）患者的左心室压力梯度（LVPG）。但是，尚不知道环苯苄胺对LVPG和左心室（LV）重塑的慢性影响。

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《Journal of cardiology》 |2016年第4期|共8页
作者
Hamada Mareomi; Ikeda Shuntaro; Ohshima Kiyotaka; Nakamura Masayuki; Kubota Norio; Ogimoto Akiyoshi; Shigematsu Yuji;
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正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词
Hypertrophic cardiomyopathy; Antiarrhythmic agent; Left ventricular pressure gradient; Left ventricular hypertrophy; Left ventricular diastolic function;

机译：肥厚型心肌病;抗心律失常药;左心室压力梯度;左心室肥大;左心室舒张功能;

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1. Impact of chronic use of cibenzoline on left ventricular pressure gradient and left ventricular remodeling in patients with hypertrophic obstructive cardiomyopathy [J] . Hamada Mareomi, Ikeda Shuntaro, Ohshima Kiyotaka, Journal of cardiology . 2016,第3a4期

机译：长期使用cibenzoline对肥厚性梗阻性心肌病患者左心室压力梯度和左心室重构的影响
2. Left ventricular endocardial pacing predicts the reduction of left ventricular outflow tract pressure gradient immediately after percutaneous transseptal myocardial ablation in patients with hypertrophic obstructive cardiomyopathy refractory to medication [J] . CHEN Shao-liang, LIN Song, WU Cheng-quan, 中华医学杂志（英文版） . 2007,第007期

机译：左心室心律起搏可预测经药物治疗难治的肥厚性梗阻性心肌病患者经皮隔隔心肌消融后左心室流出道压力梯度立即降低
3. Comparison of acute reduction in left ventricular outflow tract pressure gradient in obstructive hypertrophic cardiomyopathy by disopyramide versus pilsicainide versus cibenzoline. [J] . Kajimoto K, Imai T, Minami Y, The American Journal of Cardiology . 2010,第9期

机译：双吡amide酰胺，比西卡尼特与环苯并林在梗阻性肥厚型心肌病中左室流出道压力梯度急性降低的比较。
4. Does a Maximum Left Ventricular Thickness Greater than 30 mm Identify Patients with Hypertrophic Cardiomyopathy at Risk of Sudden Death? [C] . I. OLIVOTTO, F. CECCHI International Workshop on Cardiac Arrhythmias . 2004

机译：最大左心室厚度大于30毫米，判断患有猝死风险的肥厚性心肌病的患者吗？
5. Experimental and analytical investigation of flow pressure transients in left ventricular ejection with applications to hypertrophic cardiomyopathy [D] . Hay, Andrew Stuart 1995

机译：肥厚型心肌病在左心室射血中流动压力瞬变的实验和分析研究
6. Effect of cibenzoline on regional left ventricular function in hypertrophic obstructive cardiomyopathy [O] . Isao Kondo, Katsufumi Mlzusfflge, Shiro Nozaki, 2000

机译：环苯唑啉对肥厚性梗阻性心肌病区域左心室功能的影响
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Impact of chronic use of cibenzoline on left ventricular pressure gradient and left ventricular remodeling in patients with hypertrophic obstructive cardiomyopathy

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