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首页> 外文期刊>JAMA surgery >Safety and efficacy of implementing a multidisciplinary heart team approach for revascularization in patients with complex coronary artery disease: An observational cohort pilot study
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Safety and efficacy of implementing a multidisciplinary heart team approach for revascularization in patients with complex coronary artery disease: An observational cohort pilot study

机译:在复杂冠状动脉疾病患者中实施多学科心脏团队方法进行血运重建的安全性和有效性:一项观察性队列研究

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IMPORTANCE: Since the advent of transcatheter aortic valve replacement, the multidisciplinary heart team (MHT) approach has rapidly become the standard of care for patients undergoing the procedure. However, little is known about the potential effect of MHT on patients with coronary artery disease (CAD). OBJECTIVE: To determine the safety and efficacy of implementing the MHT approach for patients with complex CAD. DESIGN, SETTING, AND PARTICIPANTS: Observational cohort pilot study of 180 patients with CAD involving more than 1 vessel in a single major academic tertiary/quaternary medical center. From May 1, 2012, through May 31, 2013, MHT meetings were convened to discuss evidence-based management of CAD. All cases were reviewed by a team of interventional cardiologists and cardiac surgeons within 72 hours of angiography. All clinical data were reviewed by the team to adjudicate optimal treatment strategies. Final recommendations were based on a consensus decision. Outcome measures were tracked for all patients to determine the safety and efficacy profile of this pilot program. EXPOSURES: Multidisciplinary heart team meeting. MAIN OUTCOMES AND MEASURES: Thirty-day periprocedural mortality and rate of major adverse cardiac events. RESULTS: Most of the patients underwent percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG); a small percentage of patients underwent a hybrid procedure or medical management. Incidence of 30-day periprocedural mortality was low across all groups of patients (PCI group, 5 of 64 [8%]; CABG group, 1 of 87 [1%]). The rate of major adverse cardiac events during a median follow-up of 12.1 months ranged from 12 of 87 patients (14%) in the CABG group to 15 of 64 (23%) in the PCI group. CONCLUSIONS AND RELEVANCE: Outcomes of patients with complex CAD undergoing the optimal treatment strategy recommended by the MHT were similar to those of published national standards. Implementation of the MHT approach for patients with complex CAD is safe and efficacious.
机译:重要信息:自从经导管主动脉瓣置换术问世以来,多学科心脏小组(MHT)方法已迅速成为接受该手术的患者的护理标准。但是,人们对MHT对冠心病(CAD)患者的潜在作用知之甚少。目的:确定对复杂CAD患者实施MHT方法的安全性和有效性。设计,地点和参与者:在一个主要的大专/四级医疗中心,对180例CAD患者进行的观察性队列先导研究,涉及多于1个血管。从2012年5月1日到2013年5月31日,召开了MHT会议,讨论了CAD的循证管理。由介入心脏病专家和心脏外科医生组成的团队在血管造影72小时内对所有病例进行了回顾。研究小组审查了所有临床数据,以决定最佳治疗策略。最终建议基于共识决定。追踪所有患者的结局指标,以确定该试验计划的安全性和有效性。风险:多学科心脏小组会议。主要结果和措施:30天围手术期死亡率和主要不良心脏事件的发生率。结果:大多数患者接受了经皮冠状动脉介入治疗(PCI)或冠状动脉搭桥术(CABG)。一小部分患者接受了混合手术或医疗管理。在所有患者组中,30天围手术期死亡率较低(PCI组,64例中的5例[8%]; CABG组87例中的1例[1%])。中位随访时间为12.1个月,主要不良心脏事件的发生率从CABG组的87例患者中的12例(14%)到PCI组的64例中15例(23%)不等。结论和相关性:接受MHT推荐的最佳治疗策略的复杂CAD患者的结局与已发布的国家标准相似。对于复杂的CAD患者,实施MHT方法是安全有效的。

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